Plasma medicine is an emerging field of research which aims to understand and utilize the interaction of plasmas with living tissue and cells. Practical applications of plasma medicine currently being investigated include, among others: inducing rapid blood coagulation; killing bacteria, sterilizing wounds, medical instruments, and implants; and selectively modifying living cells and tissue. A panel of German and U.S. experts from the Leibniz Institute for Plasma Science and Technology (INP Greifswald), Drexel University and the NYU College of Dentistry discussed this interdisciplinary field that is beginning to have an increased impact on health care. The panel was moderated by Prof. Kurt Becker, Associate Provost for Research & Technology Initiatives and Professor of Physics at NYU-Polytechnic Institute. Nadja Dahlhaus, INP Greifswald, introduced the largest German research cluster for plasma medicine, “Campus PlasmaMed.” Prof. Gary Friedman, Drexel University, spoke about plasma medicine research at Drexel University. Dr. Van Thompson, NYU College of Dentistry, discussed plasma in dental applications. Prof. Alexander Fridman, Drexel University, and Prof. Klaus-Dieter Weltmann, INP Greifswald, addressed the status, perspectives, and challenges of plasma medicine on both sides of the Atlantic.